Unexplained IVF Failures: The Reason Why.

Unexplained IVF Failures: The Reason Why.

According to a renowned fertility specialist Dr. Geoffrey Sher, one of the most common reasons for IVF failure is poor egg quality.

 

Majority of failures are all too often due to the use of a “one size fits all” protocol for controlled ovarian stimulation (COS), which is very important in the whole process.

The success rate of IVF is higher in younger women who have normal number of eggs in their ovaries, it can however spell disaster when applied to older women, and/or those with diminished ovarian reserve.

Normally when confronted with “unexplained” IVF failures where good embryos were transferred, the question arises as to whether the problem is due to inherent egg/embryo “incompetence” or whether it is due to an implantation dysfunction.

The younger the woman and the higher the quality of available embryos the less likely it is that the fault lies with embryo “incompetence” and the greater is the likelihood that it is due to underlying implantation dysfunction.

The most common causes of implantation dysfunction are:
1. A “thin uterine lining”
2. A womb with surface lesions in the cavity (polyps, fibroids, scar tissue)
3. Immunologic implantation dysfunction (IID).

The Implantation dysfunction is a very common cause or reason of repeated “unexplained” IVF (In Vitro Fertilization) failure with good embryos. This is especially the case in mostly young ovulating women living in the world today who have normal ovarian reserve and have fertile partners.

However, failure to identify, typify, and address such issues on time is, in my opinion, an unfortunate and relatively common cause of repeated IVF failure in such women.

Chudi Godsons

Reference

http://drgeoffreysherivf.com

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